Articles from Rajesh K Kasam

The blockade of Aurora kinase B activity using Barasertib attenuates lung fibrosis

The blockade of Aurora kinase B activity using Barasertib attenuates lung fibrosis

September 17, 2020 |

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease that develops because of excessive accumulation of ECM components leading to thickening and scarring of the lungs. Aurora kinase B an enzyme involved in various cellular processes was shown to be up regulated and it’s activity can be checked by an inhibitor called Barasertib.