
LPMO-derived oligosaccharides act as powerful elicitors of plant immunity
A new discovery showed that LPMO-oxidized sugars are recognized by plants to activate strong immune responses.
Read MoreFolic Acid supplementation can reduce the transcription of Sars-Cov2
In our study, we investigated some of the high-frequency mutations of SARS-CoV-2 and performed systematic analyses of their overlay with CpG islands and inverted repeat (IR) loci. The main outcome of our study is that there is a significant presence of hot-spot mutations within both the IRs and the CpG islands.
Read MoreIntracellular conversations: Chloroplast-to-nucleus communication underpins slow-greening in an Arabidopsis mutant.
This article presents the study of chloroplast development in the Arabidopsis cue8 mutant. An elegant genetic screen developed over 20 years ago in the Chory lab to study light-induced nuclear gene expression identified as ‘CAB gene under-expressed’ or ‘cue’ mutants.
Read MoreThe blockade of Aurora kinase B activity using Barasertib attenuates lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease that develops because of excessive accumulation of ECM components leading to thickening and scarring of the lungs. Aurora kinase B an enzyme involved in various cellular processes was shown to be up regulated and it’s activity can be checked by an inhibitor called Barasertib.
Read MoreThis study would aid in unveiling the evolution of strigolactone signalling pathway in the plant development.
Read MoreThe article describes Kv3 potassium channel preferences of MNTB and LSO neurons in the auditory brainstem, thus paving the way to understanding auditory deficits in spinocerebral ataxia 13.
Read MoreProbing the mRNA 3′-end: A novel path to the gene regulation in heart
A novel anti-hypertrophy gene program was discovered, which is mediated through Star-PAP controlled selective 3’-end processing of cardiac mRNAs along with RBM10.
Read MoreMolecular determinants of RKN parasitism in susceptible and resistant tomato roots using dual RNASeq
This article is a summary of Transcriptome analysis of root-knot nematode (Meloidogyne incognita)-infected tomato (Solanum lycopersicum) roots reveals complex gene expression profiles and metabolic networks of both host and nematode during susceptible and resistance responses There are a set of definitions at the end of this post to brush up technical terms. Plant-pathogen interactions: A two-way…
Read Mored157mOptn: An isoform of mouse optineurin
d157mOptn is a novel isoform of mouse optineurin which is impaired in autophagy, unlike its full length counterpart. It is possible that d157mOptn can regulate the autophagic function of full length optineurin and might have some significance in diseased condition.
Read MoreDiscovery of genes that regulate chickpea seed development and its nutritional quality
ABI3, a transcription factor, plays a regulatory role in Seed Storage Protein accumulation in developing Chickpea seed. Over-expression of Chickpea ABI3 in Arabidopsis leads to increased protein content without significant changes in seed weight.
Read MoreRole of unique inter-motif communication in Ca2+ sensor protein Caldendrin in neuronal signaling
Caldendrin is a neuronal signalling protein shown to be important in learning and memory. In this post, the author of the scientific article explains how CDD sense the calcium by its unique mechanism.
Read More