hero image for author summary archive
illustration of LPMO-derived oligosaccharides perception.

LPMO-derived oligosaccharides act as powerful elicitors of plant immunity

By Marco Zarattini / July 12, 2021 / Comments Off on LPMO-derived oligosaccharides act as powerful elicitors of plant immunity

A new discovery showed that LPMO-oxidized sugars are recognized by plants to activate strong immune responses.

Read More
Folic Acid supplementation can reduce the transcription of Sars-Cov2

Folic Acid supplementation can reduce the transcription of Sars-Cov2

By Pratik Goswami / February 16, 2021 / Comments Off on Folic Acid supplementation can reduce the transcription of Sars-Cov2

In our study, we investigated some of the high-frequency mutations of SARS-CoV-2 and performed systematic analyses of their overlay with CpG islands and inverted repeat (IR) loci. The main outcome of our study is that there is a significant presence of hot-spot mutations within both the IRs and the CpG islands.

Read More

Intracellular conversations: Chloroplast-to-nucleus communication underpins slow-greening in an Arabidopsis mutant.

By Naresh Loudya / October 9, 2020 / Comments Off on Intracellular conversations: Chloroplast-to-nucleus communication underpins slow-greening in an Arabidopsis mutant.

This article presents the study of chloroplast development in the Arabidopsis cue8 mutant. An elegant genetic screen developed over 20 years ago in the Chory lab to study light-induced nuclear gene expression identified as ‘CAB gene under-expressed’ or ‘cue’ mutants.

Read More
The blockade of Aurora kinase B activity using Barasertib attenuates lung fibrosis

The blockade of Aurora kinase B activity using Barasertib attenuates lung fibrosis

By Rajesh K Kasam / September 17, 2020 / Comments Off on The blockade of Aurora kinase B activity using Barasertib attenuates lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease that develops because of excessive accumulation of ECM components leading to thickening and scarring of the lungs. Aurora kinase B an enzyme involved in various cellular processes was shown to be up regulated and it’s activity can be checked by an inhibitor called Barasertib.

Read More
Functional diversity of SMAX1-Like family

Functional diversity of SMAX1-Like family

By Taraka Ramji Moturu / June 7, 2020 / Comments Off on Functional diversity of SMAX1-Like family

This study would aid in unveiling the evolution of strigolactone signalling pathway in the plant development.

Read More
Title Image of Effect of Potassium Ion Channels on Hearing

Effect of Potassium Ion Channels on Hearing

By Nasreen Choudhury / June 7, 2020 / Comments Off on Effect of Potassium Ion Channels on Hearing

The article describes Kv3 potassium channel preferences of MNTB and LSO neurons in the auditory brainstem, thus paving the way to understanding auditory deficits in spinocerebral ataxia 13.

Read More
hypertrophic heart

Probing the mRNA 3′-end: A novel path to the gene regulation in heart

By Nimmy Mohan / May 14, 2020 / Comments Off on Probing the mRNA 3′-end: A novel path to the gene regulation in heart

A novel anti-hypertrophy gene program was discovered, which is mediated through Star-PAP controlled selective 3’-end processing of cardiac mRNAs along with RBM10.

Read More
title image of RKN parasitism in susceptible and resistant tomato roots

Molecular determinants of RKN parasitism in susceptible and resistant tomato roots using dual RNASeq

By Neha Shukla / April 29, 2020 / Comments Off on Molecular determinants of RKN parasitism in susceptible and resistant tomato roots using dual RNASeq

This article is a summary of Transcriptome analysis of root-knot nematode (Meloidogyne incognita)-infected tomato (Solanum lycopersicum) roots reveals complex gene expression profiles and metabolic networks of both host and nematode during susceptible and resistance responses There are a set of definitions at the end of this post to brush up technical terms. Plant-pathogen interactions: A two-way…

Read More
d157mOptn: An isoform of mouse optineurin post featured image

d157mOptn: An isoform of mouse optineurin

By Shivranjani C Moharir / February 7, 2020 / Comments Off on d157mOptn: An isoform of mouse optineurin

d157mOptn is a novel isoform of mouse optineurin which is impaired in autophagy, unlike its full length counterpart. It is possible that d157mOptn can regulate the autophagic function of full length optineurin and might have some significance in diseased condition.

Read More
Hero Image. regulation of protein accumulation in Chickpea

Discovery of genes that regulate chickpea seed development and its nutritional quality

By SubodhVerma / January 16, 2020 / Comments Off on Discovery of genes that regulate chickpea seed development and its nutritional quality

ABI3, a transcription factor, plays a regulatory role in Seed Storage Protein accumulation in developing Chickpea seed. Over-expression of Chickpea ABI3 in Arabidopsis leads to increased protein content without significant changes in seed weight.

Read More

Role of unique inter-motif communication in Ca2+ sensor protein Caldendrin in neuronal signaling

By Uday / January 7, 2020 / Comments Off on Role of unique inter-motif communication in Ca2+ sensor protein Caldendrin in neuronal signaling

Caldendrin is a neuronal signalling protein shown to be important in learning and memory. In this post, the author of the scientific article explains how CDD sense the calcium by its unique mechanism.

Read More